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It is essential for the catalytic activity of several classes of histone deacetylases (HDACs), as well as for the structural integrity and function of certain histone acetyltransferases, which together govern chromatin compaction and gene expression, and of DNA methyltransferases (DNMTs), which influence DNA methylation and processes such as lineage commitment and genomic imprinting 11
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The administration of GLP-1RA or exendin-4 to rats fed a high-fat diet resulted in an increase in the OPG/RANKL ratio and a reduction in the degree of bone loss
Magnesium research : official organ of the International Society for the Development of Research on Magnesium
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